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Search Results for " autoimmune disease "

ターゲット

阻害剤

天然化合物

108

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T5310	TR-14035	MDK-1191	Integrin
	TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).		Integrin
T12079	ML604440		Proteasome
	ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.		Proteasome
T60012	HS-243		IRAK , MAPK , CDK
	HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.		IRAK , MAPK , CDK
T38078	TLR7/8-IN-1	TLR7/8-IN-1	TLR
	TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research[1].		TLR
T80678	(S)-AK-242	(-)-Resatorvid,(S)-Resatorvid,AK-242 (S enantiomer),(-)-AK-242	Others
	(S)-AK-242 ((S)-Resatorvid) is a cytokine inhibitor used in the treatment of heart disease, autoimmune disease, and inflammatory disease.		Others
T4644	Tapinarof	GSK2894512,Benvitimod,WBI 1001	AhR , Aryl Hydrocarbon Receptor
	Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.		AhR , Aryl Hydrocarbon Receptor
T62858	HGPR91 antagonist 3		GPR
	hGPR91 antagonist 3 is an orally active, potent, and selective hGPR91 antagonist. hGPR91 antagonist 3 is used to study hypertension, autoimmune diseases, and retinal angiogenesis. hGPR91 antagonist 3 has been shown to be...		GPR
T68043	Ciamexon	Ciamexone,BM 41332,BM41332,BM-41332	Others
	Ciamexon (Ciamexone) is a novel immunomodulator that has shown promising results in experimental models of autoimmune disease with little demonstrated cytotoxicity.Ciamexon can be used to study endocrine ophthalmopathies...		Others
T78525	IRG1-IN-1		Others
	IRG1-IN-1 is an itaconic acid derivative with the ability to inhibit the activity of Immune Response Gene 1 (IRG1) and is suitable for use in the field of cancer, inflammation and autoimmune disease research.		Others
T73695	Canakinumab	ACZ 885,Ilaris	IL Receptor
	Canakinumab (ACZ885) is a recombinant human IL-1β-targeting monoclonal antibody.Canakinumab has been shown to inhibit human and chorioallantoic monkey IL-1β, with IC50 values of 43.6 and 40.8 pM, respectively.Canakinumab...		IL Receptor
T3701	MCC950	CP-456773	NOD
			NOD
T39327	Amdizalisib	Amdizalisib,HMPL-689
	Amdizalisib is a PI3K inhibitor and used for the research of inflammatory disease, autoimmune disease or cancer.
TP1362	Angiogenin (108-122)	Angiogenin 108-122
	Angiogenin (108-122) is an angiogenin peptide. Angiogenin (108-122) acts as a therapeutic agent for the prophylaxis and/or treatment of cancer, an infectious disease, a fibrotic disease, an inflammatory disease, a neurod...
T79094	Bromodomain inhibitor-12 (edisylate)		Epigenetic Reader Domain
	Bromodomain Inhibitor-12 Edisylate (example 303) serves as a bromodomain inhibitor applicable to autoimmune and inflammatory disease research [1].		Epigenetic Reader Domain
T10835L	Cletoquine oxalate	Desethylhydroxychloroquine oxalate	Others
	Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has...		Others
T79816	S1P1 agonist 6		LPL Receptor
	Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive agent in autoimmune disease research [1].		LPL Receptor
TP1320	Angiogenin (108-122) TFA (112173-49-6 free base)	Angiogenin (108-122) TFA
	Angiogenin (108-122) TFA is an angiogenin peptide.Angiogenin (108-122) acts as a therapeutic agent for the prophylaxis and/or treatment of cancer, an infectious disease, a fibrotic disease, an inflammatory disease, a neu...
T25109	ARN-6039	ARN 6039,ARN6039
	ARN-6039 is an orally available inverse agonist of RORγ for Autoimmune Neuroinflammatory Demyelinating Disease. The activity of ARN-6039 against RORγ was demonstrated in a RORγ-activated IL-17A Prom/LUCPorter assay in HE...
T79815	C-Fms-IN-14		c-Fms
	c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].		c-Fms
T75026	PROTAC TYK2 degradation agent1		PROTACs
	PROTAC TYK2 Degradation Agent1 is a potent, subtype-selective degrader of TYK2, exhibiting degradation activity with a DC50 of 14 nM. It is utilized in autoimmune disease research [1].		PROTACs
T81752	MP-PEG8-Val-Lys-Gly-7-MAD-MDCPT
	MP-PEG8-Val-Lys-Gly-7-MAD-MDCPT is an agent-linker conjugate designed for antibody-drug conjugate (ADC) applications, with potential use in cancer and autoimmune disease research.
T70870	AC430
	AC430 is a potent and specific small molecule inhibitor of janus kinase 2 (JAK2), which has been implicated as a target for therapy in both oncology and autoimmune disease. AC430 is currently being developed by Ambit. In...
T73262	C5aR-IN-3
	C5aR-IN-3, a potent C5aR inhibitor, holds potential for inflammation disease research due to its ability to counteract increased C5a levels, which are linked to autoimmune and inflammatory disorders.
T32825	L-Mevalonic acid	(S)-Mevalonic acid	Others
	L-Mevalonic acid ((S)-Mevalonic acid), a distant precursor of cholesterol, is a metabolite of the mevalonic acid pathway and is used in the study of autoimmune diseases, atherosclerosis and Alzheimer's disease.		Others
T76935	Briakinumab
	Briakinumab (ABT-874), a fully human anti-IL-12/23p40 monoclonal antibody, selectively targets and neutralizes IL-12 and IL-23. This compound is utilized in the research of various autoimmune disorders, including rheumat...
T74650	JPE-1375
	JPE-1375, a complement C5a receptor 1 (C5aR1) antagonist, effectively inhibits polymorphonuclear leukocyte mobilization (EC50=6.9 µM) and reduces TNF levels (EC50=4.5 µM) in mice, making it useful for autoimmune and infl...
T76981	Tibulizumab
	Tibulizumab (LY 3090106), a tetravalent bispecific monoclonal antibody, selectively binds to B-cell activating factor (BAFF) and IL-17A with dissociation constants (Kd) of 60 pM and 14 pM, respectively. This specificity ...
T76280	Dalazatide
	Dalazatide (ShK-186) is a specific inhibitor of the Kv1.3 potassium channel, employed in researching autoimmune conditions including multiple sclerosis (MS), lupus erythematosus, psoriasis, rheumatoid arthritis, type 1 d...
T76280L	Dalazatide TFA
	Dalazatide (ShK-186) TFA, a precise Kv1.3 potassium channel peptide inhibitor, is employed in researching autoimmune conditions, including multiple sclerosis (MS), lupus erythematosus, psoriasis, rheumatoid arthritis, ty...
T73115	(S)-HH2853
	(S)-HH2853, a pyridino-based compound featuring a five-membered aromatic ring, acts as a potent dual inhibitor of EZH1/2, displaying an IC50 of <100 nM specifically for the EZH2_Y641F mutation. This compound holds promis...
T70899	Vidofludimus hemicalcium	4sc-101 hemicalcium,SC12267 hemicalcium,4sc-101 hemicalcium ; SC12267 hemicalcium
	Vidofludimus hemicalcium (4sc-101; SC12267) is an orally active compound that acts as a dihydroorotate dehydrogenase (DHODH) inhibitor and serves as a novel modulator of the farnesoid X receptor (FXR). This immunomodulat...
T60640	SSAO inhibitor-2
	SSAO inhibitor-2 (Compound 1) can be used in the research of atherosclerosis, diabetes and its complications, obesity, stroke, chronic kidney disease, retinopathy, chronic obstructive pulmonary disease (COPD), autoimmune...
T39129	BMS-986143
	BMS-986143, an orally active, reversible BTK inhibitor with an IC50 value of 0.26 nM, is designed for autoimmune disease research. Additionally, it targets TEC, BLK, BMX, TXK, FGR, YES1, and ITK, exhibiting IC50s of 3 nM...
T60909	SSAO inhibitor-3
	SSAO inhibitor-3 (Compound 2) can be used in the study of atherosclerosis, diabetes and its complications, obesity, stroke, chronic kidney disease, retinopathy, chronic obstructive pulmonary disease (COPD), autoimmune di...
T37554	Oleyl Anilide
	AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleyl analide (OA) is a weak inhibitor of acylCoA:cholesterol acyltransfera...
T72017	6(5H)-Phenanthridinone
	6(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2. It decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells. 6(5H)-Phenanthridinone reduces NF-κ...
T36486	Benpyrine
	Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 μM. Benpyrine has the poten...
T80973	TNF-α-IN-8
	TNF-α-IN-8 (compound I-42) is an isoindole-imide-based inhibitor of tumor necrosis factor-alpha (TNF-α) with applications in researching various diseases including cancer, heart disease, osteoporosis, and autoimmune diso...
T82907	BDC2.5 Mimotope 1040-63
	BDC2.5 Mimotope 1040-63 is a biologically active peptide employed in the investigation of type 1 diabetes (T1D), an autoimmune disease where T cells induce destruction of pancreatic islet β cells. This mimotope, originat...
T69600	Spermidine-d6
	Spermidine-d6 is intended for use as an internal standard for the quantification of spermidine by GC- or LC-MS. Spermidine is an endogenous polyamine. It is formed from putrescine by spermidine synthase. Spermidine (25 µ...
T37419	Zetomipzomib
	KZR-616, a first-in-class inhibitor of the immunoproteasome, selectively targets the LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50: 131/179 nM=hLMP7/mLMP7) subunits of the immunoproteasome. KZR-616 has the potential f...
T81609	Omega-3 Arachidonic acid ethyl ester	(all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester,ω-3 Arachidonic acid ethyl ester
	Omega-3 Arachidonic Acid ethyl ester, a rare polyunsaturated fatty acid with limited presence in dietary sources, is crucial for infant growth and development and offers protection against heart disease, blood clots, hig...
T36578	Boc-Lys(Ac)-AMC
	Commendamide (N-acyl-3-hydroxypalmitoyl-glycine) is a newly discovered GPCR G2A/GPR132 agonist (EC50=11.8 μM) that isolated from Bacteroides vulgatus. [1] G2A/GPR132 belongs to the guanine nucleotide-binding protein (G p...

Compounds

Target: IRAK, MAPK, CDK

Synonym: (-)-Resatorvid,(S)-Resatorvid,AK-242 (S enantiomer),(-)-AK-242

Target: Others

Tapinarof

T4644

Synonym: GSK2894512,Benvitimod,WBI 1001

Target: AhR, Aryl Hydrocarbon Receptor

Synonym: Ciamexone,BM 41332,BM41332,BM-41332

Synonym: ACZ 885,Ilaris

Synonym: Amdizalisib,HMPL-689

Target:

Angiogenin (108-122)

TP1362

Synonym: Angiogenin 108-122

Target:

Bromodomain inhibitor-12 (edisylate)

T79094

Synonym:

Target: Epigenetic Reader Domain

Cletoquine oxalate

T10835L

Synonym: Desethylhydroxychloroquine oxalate

Angiogenin (108-122) TFA (112173-49-6 free base)

TP1320

Synonym: Angiogenin (108-122) TFA

Target:

ARN-6039

T25109

Synonym: ARN 6039,ARN6039

PROTAC TYK2 degradation agent1

T75026

Synonym:

Target: PROTACs

MP-PEG8-Val-Lys-Gly-7-MAD-MDCPT

Synonym: (S)-Mevalonic acid

Vidofludimus hemicalcium

T70899

Synonym: 4sc-101 hemicalcium,SC12267 hemicalcium,4sc-101 hemicalcium ; SC12267 hemicalcium

6(5H)-Phenanthridinone

BDC2.5 Mimotope 1040-63

omega-3 Arachidonic acid ethyl ester

T81609

Synonym: (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester,ω-3 Arachidonic acid ethyl ester

カタログ番号	製品名	別名	ターゲット
T10835	Cletoquine	Desethylhydroxychloroquine	Parasite , Antifection
	Cletoquine is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune disease treatme...		Parasite , Antifection
T3877	Esculentoside A		NF-κB , COX
	Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmun...		NF-κB , COX

天然物製品

Cletoquine

T10835

Synonym: Desethylhydroxychloroquine

Target: Parasite, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02970	CXCL10 Protein, Human, Recombinant	Human	E. coli
	(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor couple...
TMPY-05446	CD200 Protein, Human, Recombinant (hFc)	Human	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-03855	DNase I Protein, Human, Recombinant (His)	Human	HEK293
	DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phos...
TMPY-05480	IL-21R Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamil...
TMPY-04832	OX40L/TNFSF4 Protein, Human, Recombinant (hFc)	Human	HEK293
	OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-med...
TMPY-00418	IL-21R Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamil...
TMPY-01934	IL-21R Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamil...
TMPY-05274	IL-23R Protein, Human, Recombinant (His)	Human	HEK293
	IL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isofo...
TMPY-02779	Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)	Human	Baculovirus-Insect Cells
	Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoant...
TMPY-00705	CD30L Protein, Human, Recombinant (hFc)	Human	HEK293
	CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specific ligand for CD30/TNFRSF8 originally described as a cell s...
TMPY-04289	CD30L Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specific ligand for CD30/TNFRSF8 originally described as a cell s...
TMPY-04483	IRAK4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPY-00981	ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK)	Human	HEK293
	Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. IC...
TMPY-01621	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)	Human	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPY-05227	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPY-03467	IFN-beta Protein, Mouse, Recombinant	Mouse	HEK293
	Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras...
TMPY-00831	IFN-beta Protein, Human, Recombinant (hFc)	Human	HEK293
	Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras...
TMPY-03145	IFN-beta Protein, Human, Recombinant	Human	CHO
	Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras...
TMPY-01142	ICAM-1/CD54 Protein, Human, Recombinant (His)	Human	HEK293
	Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. IC...
TMPY-05017	ICAM-1/CD54 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. IC...
TMPY-01349	ICAM-1/CD54 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. IC...
TMPY-04345	PD-L1 Protein, Rat, Recombinant (His)	Rat	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-03670	PD-L1 Protein, Cynomolgus/Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-01155	PD-L1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-04949	PD-L1 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-05208	PD-L1 Protein, Human, Recombinant	Human	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-04343	PD-L1 Protein, Human, Recombinant (His)	Human	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-00237	PD-L1 Protein, Canine, Recombinant (hFc)	Canine	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-00021	PADI4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase f...
TMPY-01028	Ficolin 1/FCN1 Protein, Human, Recombinant (His)	Human	HEK293
	Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. The Ficolin family of proteins are characterized by the presence of a leader ...
TMPY-02952	SIAE Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of th...
TMPJ-00532	PADI4 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyz...
TMPY-04943	CXCL10 Protein, Rat, Recombinant (His)	Rat	Yeast
	(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor couple...
TMPY-05638	CD200 Protein, Human, Recombinant (hFc & Avi)	Human	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-03380	CD200 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPH-01853	Perforin-1/PRF1 Protein, Human, Recombinant (His & MBP)	Human	Baculovirus
	Pore-forming protein that plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-s...
TMPH-01854	Perforin-1/PRF1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Pore-forming protein that plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-s...
TMPY-03595	CD200 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-01071	CD200 Protein, Human, Recombinant (His)	Human	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-06791	CD200 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-02193	GOLPH2/GOLM1 Protein, Human, Recombinant (His)	Human	HEK293
	Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2, and GOLM1, is a protein that belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in the colo...
TMPY-03266	COL4A3BP Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	COL4A3BP is a member of the StarD2 subfamily. It contains a pleckstrin homology domain at its amino terminus and a START domain towards the end of the molecule. COL4A3BP has a lipid-binding domain that mediates intrac...
TMPK-00874	Thyroid Peroxidase Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormon...
TMPY-01160	CD200 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPJ-00848	NCF1 Protein, Human, Recombinant (His)	Human	E. coli
	Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a mem...
TMPY-06018	OX40L/TNFSF4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-med...
TMPY-04981	OX40L/TNFSF4 Protein, Mouse, Recombinant (mFc)	Mouse	HEK293
	OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-med...
TMPJ-00637	PD-L1 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
	CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, C...
TMPY-01654	ITCH Protein, Human, Recombinant (aa 526-903)	Human	E. coli
	E3 ubiquitin-protein ligase Itchy homolog, also known as Atrophin-1-interacting protein 4, NFE2-associated polypeptide 1, NAPP1, and ITCH, is a cell membrane protein that contains one C2 domain, one HECT (E6AP-type E3 ub...
TMPY-00260	IL-21R Protein, Cynomolgus, Rhesus, Recombinant (hFc)	Cynomolgus,Rhesus	HEK293
	Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamil...
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